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Telomeres and telomere dynamics: relevance to cancers of the gastrointestinal tract

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Wikipedia:Unusual place names - Wikipedia

Aberrations in telomere length and telomere maintenance contribute to cancer development. In this article, we review basic principles of telomere length in normal and tumor tissue and the presence of the two main telomere maintenance pathways as they pertain to GI tract cancer. Peripheral blood telomeres are shorter in patients with many types of GI tract cancers. Telomere length in tumor DNA also appears to shorten early in cancer development. Tumor telomere shortening is often accompanied by telomerase activation to protect genetically damaged DNA from normal cell senescence or apoptosis, allowing immortalized but damaged DNA to persist.
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Wikipedia:Unusual place names

This page is meant for Wikipedians to list articles about places with unusual names. Taumatawhakatangihangakoauauotamateapokaiwhenuakitanatahu : A small hill with a big name in New Zealand. From Wikipedia, the free encyclopedia. This page contains material that is kept because it is considered humorous.
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Continue to access RSC content when you are not at your institution. Follow our step-by-step guide. The ideal way to assess aptamer affinity is when both aptamer and target are in a native state, without the unpredictable interference associated with labelling and surface immobilization. Ideally, such a solution-phase assay should also be high-throughput, in order to accelerate aptamer identification, binding site study, and engineering for various downstream applications. So far, only isothermal titration calorimetry ITC enables label-free solution-phase affinity measurements, but with low-throughput and the need of large amount of samples.
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